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The number of glucose molecules condensed on glycated bovine serum albumin have been easily determined by means of matrix-assisted laser desorption/ionization mass spectrometry. Measurements were carried out on samples from incubation of the protein with glucose at different concentrations (0.02 M, 0.2 M, 2 M and 5 M). A clear increase in molecular mass of(More)
Various techniques are employed to determine the amounts, retention, and distribution of radioactivity in human subjects in vivo. The principal method is gamma-ray spectrometry with large NaI(Tl) scintillation crystals ("whole-body counting"). The geometries used include an arc of 1.5-m radius in which all parts of the body are roughly equidistant from the(More)
Source: Hacker, Eddy and Lewis (2002) A visual appreciation of Keane’s two-dimensional (m=2) bump function may be obtained from the graphical presentation (Fig.-1; Hacker et al., 2002). As the dimension (m) grows larger, the optimum value of the function becomes more and more difficult to obtain. Keane (1994) observed that for m=20 the value of min[f(x)](More)
In the records of 5,058 persons with therapeutic or occupational exposure to radium, 21 patients with carcinoma of the mastoid and 11 with malignant tumors of the paranasal sinuses were identified. Tumor induction times were 21-50 years for mastoid tumors (median, 33) and 19-52 years for paranasal sinus tumors (median, 34). Dosimetric data are given for the(More)
Despite the dramatic fall in ischemic heart disease (IHD) mortality rates over the last 3 decades, it remains the number one cause of death in the United States, and one of the most frequent indications for care by the US Department of Veterans Affairs. National practice guidelines have been developed and disseminated both by societies that specialize in(More)
An unusually protracted retention of uranium in the chests of certain workers at a uranium processing plant has been reported in the literature. This finding has implications for the protection of current uranium workers and for health-effects studies of early workers. It is shown that the limited data obtained postmortem that have been reported do not(More)
In the past few years, various investigators have collected information on naturally occurring and radiation-induced bone tumors. This paper compares (a) the type and distribution of naturally occurring bone tumors in man and dog, (b) the type and distribution of bone tumors induced in man and dog by bone-seeking radionuclides, and (c) the skeletal(More)