A K Azad Khan

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Three vignettes exemplify the potential of combining EM and X-ray crystallographic data with molecular dynamics (MD) simulation to explore the architecture, dynamics and functional properties of multicomponent, macromolecular complexes. The first two describe how EM and X-ray crystallography were used to solve structures of the ribosome and the Arp2/3-actin(More)
In this work, electron paramagnetic resonance (EPR) spectroscopy and X-ray crystallography were used to examine the origins of EPR line shapes from spin-labels at the protein-lipid interface on the β-barrel membrane protein BtuB. Two atomic-resolution structures were obtained for the methanethiosulfonate spin-label derivatized to cysteines on the(More)
1-Aminoindanes are generated from allyl diphenylglycinate imines employing a "one-pot" palladium-catalyzed decarboxylative allylation-Heck cyclization cascade. Variation of both the aryl and allyl moieties leads to a diverse range of polycyclic imines, amenable to the synthesis of natural products and other biologically relevant small molecules.
Aims: This study was carried out to explore the prevalence of HBV and HCV infections among type 2 diabetes mellitus (T2DM) patients and risk factors. This crosssectional study was conducted at BIRDEM General Hospital, Dhaka, Bangladesh between January 2012 and March 2013. Subjects and Methods: A total of 1024 type 2 diabetics were included. Wellstructured(More)
New pH-sensitive lipids were synthesized and utilized in formulations of liposomes suitable for controlled drug release. These liposomes contain various amounts of NaCl in the internal aqueous compartments. The release of the drug model is triggered by an application of HCl cotransporter and exogenous physiologically relevant NaCl solution. HCl(More)
In this paper we are trying to propose a system that can run in parallel with the usual search engine to provide the user with unified and summarized information. Our system will relieve the user of manual accessing of each of the web links that is produced by the search result of a search engine. To implement such feature in the search process, here we(More)
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