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This article outlines some of the principal issues in the development of numerical methods for the prediction of flows over aircraft and their use in the design process. These include the choice of an appropriate mathematical model, the design of shock-capturing algorithms, the treatment of complex geometric configurations, and shape modifications to(More)
A direct and quantitative study of the effects of sublingually administered nitroglycerin on the major determinants of myocardial oxygen consumption was carried out in 10 patients, 7 with coronary artery disease. Left ventricular wall tension, estimates of the contractile state and heart rate were studied directly using simultaneous pressure measurements(More)