A.J. Verbout

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OBJECTIVES: We previously demonstrated that diaspirin crosslinked hemoglobin (DCLHb, Baxter Healthcare Corp.) improves systemic oxygen uptake in sepsis. Therefore, our objective was to study the effects of DCLHb on microcirculatory blood flow in septic rats. DESIGN: Prospective and randomized experimental study in a university-affiliated laboratory.(More)
OBJECTIVES: Inflammatory mediators appear to play key role in the development of adult respiratory distress syndrome (ARDS) in critically ill patients. Cytokines involved in the early phase include tumor necrosis factor alpha (TNFa) and selected interleukins. Experimental infusion of TNFa has been shown to cause ARDS and increased concentration of cytokines(More)
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