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This study tests the hypothesis that if the fast twitch muscles in a synergistic group were more susceptible to ischemia/reperfusion injury, then the slow twitch muscle would compensate functionally during recovery. Rat hindlimb fast twitch gastrocnemius and plantaris muscles and slow twitch soleus muscle were studied. In the experimental (E) group of rats,(More)
BACKGROUND Advanced motorized prosthetic devices are currently controlled by EMG signals generated by residual muscles and recorded by surface electrodes on the skin. These surface recordings are often inconsistent and unreliable, leading to high prosthetic abandonment rates for individuals with upper limb amputation. Surface electrodes are limited because(More)
T-1249 is a peptide that inhibits the fusion of HIV envelope with the target cell membrane. Recent results indicate that T-1249, as in the case of related inhibitor peptide T-20 (enfuvirtide), interacts with membranes, more extensively in the bilayer liquid disordered phase than in the liquid ordered state, which could be linked to its effectiveness.(More)
Although bipolar cautery was designed to minimize trauma to the central nervous system, little is known about the effects of bipolar cautery on peripheral nerve tissue. This experiment was designed to study the effect of direct bipolar cautery on a peripheral nerve and the muscles innervated by that nerve. Lewis rats (n = 200) were assigned to five(More)
It has been estimated that more than 1.6 million individuals in the United States have undergone at least one amputation. The literature abounds with research of the classifications of such injuries, their etiologies, epidemiolo-gies, treatment regimens, average age of onset (average age of amputation), and much more. The subpopulation that is often(More)
Density functional theory (DFT) calculations have been carried out to investigate the switching of the second-order nonlinear optical (NLO) properties of η(5)-monocyclopentadienyliron(II) and ruthenium(II) model complexes presenting 5-(3-(thiophen-2-yl)benzo[c]thiophen-1-yl)thiophene-2-carbonitrile as a ligand. The switching properties were induced by redox(More)
An apparatus, consisting of a pair of small strain gauge transducers, was designed for the simultaneous assessment of isometric contractile function in two muscles, composed of a predominance of either fast- or slow-twitch fibers, and within a single rat hindlimb in situ. This facilitates assessment of mechanical performance of two separate muscles under(More)
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