A J Dowding

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We have immunohistochemically characterized the forms and distribution of microglia--the macrophages of the CNS--in fish, using a new monoclonal antibody (mAb), FL.1. This mAb specifically reacts with resident macrophages throughout the body in Oreochromine fish, including Kuppfer cells, gut-associated myeloid cells, and peritoneal macrophages, as well as(More)
As shown by staining with a monoclonal antibody against fish CD45, leukocytes are present in very large numbers in the fish central nervous system. Their subtypes were distinguished by electron microscopy and found to include all major hematogenous forms except thrombocytes, the most numerous being tissue macrophages and lymphocytes. As a population, they(More)
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