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In the present work, the chromosomal DNA isolated from the bacterium E. coli was treated with methylene blue. Formation of a heat-stable complex with methylene blue and E. coli chromosomal DNA, has changed the hyperchromic characteristics of E. coli DNA to some extent. It seemed possible that in vivo binding of the dye with DNA may inhibit the separation of(More)
The mutagenic effects of 4 insecticides, i.e., bioallethrin, tetramethrin, propoxur, lethane and three commercial formulation of insecticides i.e. asbo, formulation I, formulation II was determined in a standard Salmonella typhimurium assay with the use of strains TA 98 and TA 100. Bioallethrin was found to be a weak mutagen in the TA 100 and TA 98 strains(More)
The mutagenicity of 4 azo dyes (Ponceau 4R, Amaranth, Sunset Yellow FCF and Tartrazine) that are widely used to color food has been evaluated. They were tested for mutagenicity in the Salmonella typhimurium plate-incorporation and preincubation assays. The standard plate-incorporation and preincubation assays performed directly on the dyes in the absence(More)
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