A Iu Nemirovskiĭ

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In experiments on rats it was shown that the neuroleptics droperidol (0.6 mg/kg) and aminazin (10 mg/kg) can potentiate the analgetic action of the endogenous morphine-like pentapeptide leucin-enkephalin administered into the brain ventricles at a dose of 50 micrograms. A statistically significant increase in the analgetic activity lf leucin-enkephalin(More)
Magnetically carried microspheres were used to investigate whether the curare-like drugs can be selectively transported to the muscles of one of the limbs of the cat. Pyrocurine and diadonium incorporated in such microspheres primarily suppressed neuromuscular transmission in the limb placed in magnetic field as compared with the control placed outside the(More)
Two series of experiments were performed to study the effects of oxotremorine (5, 10 and 20 micrograms/kg), arecoline (0.25, 0.5 and 1.0 mg/kg), pilocarpine (5, 10 and 20 mg/kg) and aceclidine (0.25, 0.5 and 1.0 mg/kg) injected intravenously on nociceptive transmission in the spinal cord of spinal rats. It was established that the m-cholinomimetics inhibit(More)
The experiments on cats have shown that liposomes containing ferrocolloid and neuromuscular blocking agents (diadonium or dipyronium) cause selective muscle relaxation in the animal limb placed into the magnetic field, compared to the control limb kept outside the field. This effect was not related to the action of the magnetic field per se on neuromuscular(More)
The effect of anticholinesterases physostigmine and galanthamine on spontaneous and intraarterial bradykinin-induced bioelectrical activity in the ventrolateral tracts of the spinal cord in spinal rats was studied. Physostigmine (1, 2 and 4 micrograms) and galanthamine (25, 50 and 100 micrograms) administered intrathecally were found to produce(More)
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