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Our previous work has demonstrated the roles played by L-type Voltage Gated Calcium Channels (VGCC) in regulating Mycobacterium tuberculosis (M. tb) survival and pathogenesis. Here we decipher mechanisms and pathways engaged by the pathogen to regulate VGCC expression in macrophages. We show that M. tb and its antigen Rv3416 use phospho-CREB (pCREB),(More)
Image segmentation is one of the significant computational applications of the biomedical field. Automated computational methodologies are highly preferred for medical image segmentation since these techniques are immune to human perception error. Artificial intelligence (AI)-based techniques are often used for this process since they are superior to other(More)
The emergence of drug resistant strains of Mycobacterium tuberculosis (M. tuberculosis) together with reports of co-infections with the human immunodeficiency virus (HIV) has renewed interest to better understand the intricate mechanisms prevalent during co-infections. In this study we report a synergistic effect of M. tuberculosis and HIV-1, and their(More)
Conventional controllers like Proportional Derivative (PD), Proportional Integral (PI) and Proportional Integral Derivative (PID) controllers were used in implementing Velocity Control Mode (VCM) in Cruise Control (CC) and Adaptive Cruise control (ACC) vehicles. Transition that occur in "resume mode" of CC and transitions that occur during switching from(More)
This research compares the application of metaheuristics to solve the problem of real-time task assignment in two different heterogeneous multiprocessor systems. The difference in system is made by the arrangement of the processors. The metaheuristics used to solve the problem are Novel Binary Particle Swarm Optimization (Novel BPSO) and Modified Binary(More)
Adaptive Cruise Control is used in vehicles for giving support to the drivers and to circumvent rear end collision. Due to the presence of nonlinearity in the vehicle (system), it is difficult to design an exact mathematical model of the system. Heuristic based fuzzy logic controller with optimized rule base, which does not require accurate mathematical(More)