A. I. Esakov

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Studies have been made of the effect of exogeneous serotonin on responses of taste receptors recorded from the hypoglossal nerve during adequate stimulation. It was shown that serotonin evokes afferent discharge in this nerve and significantly increases responses of taste receptors. Stimulating effect of serotonin appears 15-20 min after its application and(More)
An attempt was made to identify specific monoamines contained in the dumb-bell shape cells of the frog taste bud by means of histochemical analysis. It was shown by fluorescent microscopy that preliminary administration of exogenous serotonin into the blood channel of frog tongue resulted in a sharp increase of specific fluorescence of the dumb-bell shape(More)
The object of the present investigation was t o asce r t a in whether impulses can spread ant idromical ly during adequate st imulation of the taste receptors . A positive answer to this question would make it poss i ble to postnlate the existence of interact ion between taste receptors analogous to that found between the photoreceptors of inver tebra tes(More)
The effect of the intraperitoneal injection of 10(-5) M cholecystokinin-pancreozimin solution on the taste total impulse activity of the rat chorda tympani was studied. The taste responses to sodium chloride and sucrose increased within 5 min and responses to quinine increased within 30 sec after the peptide injection. Responses to citric acid solution did(More)
A clearly positive correlation between the level of substance P (SP) in the taste nerves and cellular serotonin content in the taste buds has been established using fluorescent-histochemical technique. In chronic SP deficiency caused by capsaicin, cellular serotonin content was considerably decreased due to the disturbances in its synthesis and uptake. The(More)
In investigations of gustatory reception, efferent regulation of the activity of the taste receptors in the f rog ' s tongue was shown to be possible [1-3]. Spike activity in the taste f ibers was studied in those investigations, but on this basis alone it was impossible to state whether the change in the charac te r of the afferent flow of impulses was the(More)
The effect of substance P (SP) on monoamine-containing cells of the frog taste buds was studied by fluorescent microscopy. Intraperitoneal injection of SP resulted in a gradual increase of cell serotonin content. In monoamine deficiency caused by previous injection of rausedyl, SP favoured the recovery of the serotonin level to initial. When SP and rausedyl(More)
By an e lect rophysiological method of recording afferent activity of a cutaneous nerve evoked by pinpoint st imulation of the skin, resu l t s were obtained indicating the existence of ref lex interact ion between tactile r ecep to r s of symmet r i ca l skin a reas . Spinal neuron. ~. at the level of segment 8-9 and also efferent somatic and sympathetic(More)
Electrical stimulation of the gustatory nerve is accompanied by the development of a positive electrical potential on the outer surface of the tongue (relative to its inner layers). The amplitude and steepness of rise of this potential increase whereas the latent period decreases with an increase in the frequency of stimulation. The response arises in the(More)