A I Baĭnova

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The 40-day oral administration of 5, 10, and 50 mg/kg chlordimeform to male rats moderately decreased monoamine oxidase activity (MAO) in the brain, liver, and serum, determined with the substrates kynuramine, tyramine, tryptamine, serotonin, dopamine, and benzylamine. The enzyme was inhibited predominantly in the liver. The study of MAO inhibition after 10(More)
The effect of simultaneous exposure to noise and dimethylformamide (DMF), noise and xylol and also vibration and lead on the metabolism of the myocardium of albino rats was studied. Combined effect of the factors was examined by the method of bifactorial design of the experiment. The animals were exposed to noise, intensity 46, 85 and 95 dB (2 and 4 hours),(More)
Repeated oral toxicity was assayed in albino rats of either sex, receiving every day 70 mg/kg of Ramrod for 4 months (group I) and everyday, but on alternate weeks-140 mg/kg (group II). A third experimental group of animals received daily 70 mg/kg of Ramrod on alternate weeks for 8 months. In comparison with the respective pure control groups of rats, those(More)
Two dipyridilium herbicides--Gramoxon and Reglon, at doses 1/3, 1/10 and 1/20 LD50--are administered to rats per os, daily over a period of one month. The values of the cumulation coefficients (CC) are calculated on the ground of lethality data. The clinical picture of intoxication caused by the above preparations is also studied. Daily, one-month long(More)
Reglon (20 per cent dikwad dibromide) is an extensively used herbioide and desiccant. During acute and chronic inhalatory experiments on white rats, using 4--hour exposure to water aerosols, determination is made of the acute LC50 -- 83 mg/m3, of the acute threshold concentration - 9.9 mg/m3 acute substance, as well as of the chronic threshold concentration(More)
Medical and clinico-laboratory examinations were performed of thermoelectric power station (TES) workers who were exposed to the hazardous factors related to the technological process and contamination substances transferred from other industrial sites. Following prepathologic and pathologic states were registered: respiratory functional disorders, ischemic(More)
Studies are performed on 44 workers, engaged in the production of ethylenediamine. The principle chemical noxae are: ammonia, ethylenediamine, dichloroethane, analogues of ethylenediamine, vinylchloride, sodium hydrate etc. The average concentrations of these compounds surpass the admissible norms for the air of the working environment. The biochemical(More)
In an interdisciplinary approach the exposure to lead and cadmium of the population living in the vicinity of a Bulgarian non-ferrous metallurgical plant was studied to determine the routes of exposure. Two exposed villages situated 4 and 6 km SW and W, respectively,--in the plume of the plant's emissions--and a village for comparison situated 14 km SE of(More)
The use of styrene in the production and processing of polymers, varnishes and paints is a prerequisite for a broad skin contact with the solvent, hence conditions for occupational effect on the workers, manifested with frequent contact toxic dermatitis. That determined the scope of this work, aiming at the specifying of the occupational risk in case of(More)