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To assess developmental and aging changes in human sensory systems, components of short-latency somatosensory, brain-stem auditory and pattern-reversal visual evoked potentials, thought to originate in specific structures of these systems, were recorded in 286 normal subjects ranging in age from 4 to 95 years. Analysis was primarily restricted to peak and(More)
Simultaneous recording of the somatosensory evoked potential (SEP) from the neck and from the scalp allows investigation of conduction of somatosensory impulses within the central nervous system alone. The early components of the SEP produced by stimulation of the median nerve at the wrist were recorded from standardized electrode locations on the scalp and(More)
This paper describes the experiences of the OGSA-DAI team in designing and building a database access layer using the OGSI and the emerging DAIS GGF recommendations. This middleware is designed for enabling other UK e-Science projects that require database access and providing the basic primitives for higher-level services such as Distributed Query(More)
Somatosensory evoked potentials (SEPs) following median nerve stimulation were recorded over Erb's point (N10), neck (N13) and scalp (N20) of 17 neurologically normal patients during hypothermic cardiopulmonary bypass. Anesthesia was induced with fentanyl and 100% oxygen, and supplemented with isoflurane as necessary. All 3 SEPs were recorded at esophageal(More)
Pattern visual evoked potentials (PVEPs) were recorded at 5 levels of luminance from 26 patients with multiple sclerosis and from age-matched normal subjects. In normal subjects, the latency of both the major positive peak (P100) and the early positive peak (P60) was an inverse logarithmic function of pattern luminance. The increase in latency per unit log(More)
The relative prognostic value of short-latency somatosensory evoked potentials (SEPs) and brain-stem auditory evoked potentials (BAEPs) was assessed in 35 patients with post-traumatic coma. Analysis of the evoked potentials was restricted to those recorded within the first 4 days following head injury. Abnormal SEPs were defined as an increase in central(More)
OGSA-DAI is a widely used middleware infrastructure, aligned with the Global Grid Forum's (GGF) OGSA vision, to facilitate uniform access to data resources using a service-oriented architecture (SOA). It is intended to provide a reference implementation of WS-DAI. Initially OGSA-DAI was based on the OGSI infrastructure but recent releases support WS-I,(More)
Somatosensory conduction time between the dorsal column nuclei and the cerebral cortex may be measured following median nerve stimulation by recording evoked potentials from both scalp and neck. Central conduction times were significantly increased relative to normal (5.6 +/ 0.5 msec) in 11 of 24 comatose patients. Results within 10 and 35 days of onset of(More)