A. Heifetz

Learn More
Recently, there has been a major thrust to understand biological processes at the nanoscale. Optical microscopy has been exceedingly useful in imaging cell microarchitecture. Characterization of cell organization at the nanoscale, however, has been stymied by the lack of practical means of cell analysis at these small scales. To address this need, we(More)
Geometric complementarity is the most dominant term in protein-protein docking and therefore, a good geometric representation of the molecules, which takes into account the flexibility of surface residues, is desirable. We present a modified geometric representation of the molecular surface that down-weighs the contribution of specified parts of the surface(More)
This paper reviews the substantial body of literature emerging since 2004 concerning photonic nanojets. The photonic nanojet is a narrow, high-intensity, non-evanescent light beam that can propagate over a distance longer than the wavelength λ after emerging from the shadow-side surface of an illuminated lossless dielectric microcylinder or microsphere of(More)
We submitted predictions for all seven targets in the CAPRI experiment. For four targets, our submitted models included acceptable, medium accuracy predictions of the structures of the complexes, and for a fifth target we identified the location of the binding site of one of the molecules. We used a weighted-geometric docking algorithm in which contacts(More)
The authors report experimental confirmation of backscattering enhancement induced by a photonic jet emerging from a dielectric sphere, a phenomenon recently predicted by theoretical solutions of Maxwell's equations. To permit relatively straightforward laboratory measurements at microwave frequencies rather than visible light, they appropriately scaled the(More)
We theoretically investigate light scattering from a bi-sphere system consisting of a gold nanosphere and a lossless dielectric microsphere illuminated at a resonant optical wavelength of the microsphere. Using generalized multisphere Mie theory, we find that a gold nanosphere 100 times smaller than the dielectric microsphere can be detected with a(More)
We report a means to detect deeply subwavelength pits in optical data-storage media by employing the recently observed giant backscattering perturbation phenomenon of the photonic jet. We conducted microwave experiments with dimensionally scaled-up pits and lands in a simulated optical data-storage device. These measurements were backed up by(More)
Partial Wave Spectroscopic (PWS) Microscopy has proven effective at detecting nanoscale hallmarks of carcinogenesis in histologically normal-appearing cells. The current method of data analysis requires acquisition of a three-dimensional data cube, consisting of multiple images taken at different illumination wavelengths, limiting the technique to data(More)
Photonic Nanojets are highly localized wave fields emerging directly behind dielectric microspheres; if suitably illuminated. In this contribution we reveal how different illumination conditions can be used to engineer the photonic Nanojets by measuring them in amplitude and phase with a high resolution interference microscope. We investigate how the(More)
An optically illuminated micron-scale dielectric sphere can generate a photonic nanojet – a nonresonant propagating beam phenomenon of high amplitude, narrow waist, and substantial sensitivity to the presence of nanometer-scale particles and geometric features located within the beam. Via three-dimensional finite-difference time-domain computational(More)