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Although recent evidence indicated that the production of reactive oxygen species (ROS) by human spermatozoa may be involved in the regulation of capacitation, very little is known about the role of ROS in the acrosome reaction. To address this issue, Percoll-washed spermatozoa were incubated in Ham's F-10 medium in the absence (no capacitation) or presence(More)
Recent evidence indicated that human sperm capacitation is associated with an increased production of superoxide anion (O2.-). To further study the role and importance of O2.- in capacitation, we investigated whether the O2.- generation is a general feature of capacitating spermatozoa, irrespective of the inducer used, and is correlated with capacitation(More)
Invasive micropapillary carcinoma (IMC) of the breast is a rare variant of the invasive ductal carcinoma; it is characterized by a unique histology and an extremely high-incidence of lymph node metastases (95%). Histologically, IMC of the breast has been well described but it remains insufficiently recognized in clinical practice. Carcinomas with an IMC(More)
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