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The newly formed bone, both cortical and cancellous, consists of extracellular matrix (Piez and Reddi, 1984) Center for Tissue Regeneration and Repair and Department of Orthopaedic Surgery with a constellation of constituents (Table 1) that is min-eralized. Bone is akin to reinforced concrete. The fibrillar collagens with associated supramolecular assembly(More)
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