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Using microarray technology, we investigated whether the gene expression profile in white blood cells could be used as a fingerprint of different disease states. Adult rats were subjected to ischemic strokes, hemorrhagic strokes, sham surgeries, kainate-induced seizures, hypoxia, or insulin-induced hypoglycemia, and compared with controls. The white blood(More)
The receptor for advanced glycation end products (RAGE), a multi-ligand member of the immunoglobulin superfamily of cell surface molecules, interacts with distinct molecules implicated in homeostasis, development and inflammation, and certain diseases such as diabetes and Alzheimer's disease. Engagement of RAGE by a ligand triggers activation of key cell(More)
The current study determined whether short durations of ischemia that produce ischemia-induced tolerance stimulate glial proliferation in brain. Adult male gerbils were injected with BrdU (50 mg/kg) and dividing cells were detected using immunocytochemistry after sham operations, 2.5 or 5 minutes of global ischemia, or ischemia-induced tolerance. The(More)
The Cryogenic Dark Matter Search (CDMS) employs Ge and Si detectors to search for weakly interacting massive particles (WIMPs) via their elastic-scattering interactions with nuclei while discriminating against interactions of background particles. CDMS data, accounting for the neutron background, give limits on the spin-independent WIMP-nucleon(More)
We present a measurement of the time-dependent CP-violating (CPV) asymmetries in B0-->K(0)(S)pi(0) decays based on 124x10(6) Upsilon(4S)-->BB decays collected with the BABAR detector at the PEP-II asymmetric-energy B factory at SLAC. In a sample containing 122+/-16 signal decays, we obtain the magnitudes of the direct CPV asymmetry(More)
Integrin α11β1 is a stromal cell-specific receptor for fibrillar collagens and is overexpressed in carcinoma-associated fibroblasts (CAFs). We have investigated its direct role in cancer progression by generating severe combined immune deficient (SCID) mice deficient in integrin α11 (α11) expression. The growth of A549 lung adenocarcinoma cells and two(More)
(nominal inner diameter: 0.6 mm) needles into rotating 40 wt.-% PEI (branched; average molecular weight, M w ~ 25 000; water-free; Aldrich) solutions in methanol. The SWNT/PEI composite fibers were characterized by SEM (LEO 1590 VP microscope) and micro-Raman spectroscopy (Jobin± Yvon Horiba high-resolution LabRam micro-Raman spectrometer; helium±neon(More)
We present an updated measurement of time-dependent CP-violating asymmetries in neutral B decays with the BABAR detector at the PEP-II asymmetric B Factory at SLAC. This result uses an additional sample of Upsilon(4S) decays collected in 2001, bringing the data available to 32 x 10(6) BB macro pairs. We select events in which one neutral B meson is fully(More)
the filter were measured using condensation particle counters (TSI Inc. model 3022A). Submicrometer particles entering the counters are grown into micrometer sized droplets by condensation of a supersatu-rated vapor of 1-butanol onto the particles, then counted by laser light scattering. The particle concentrations were averaged over ten measurements at(More)
1 H and 13 C NMR spectra were recorded in deuterated solvents, such as CD 2 Cl 2 , on a Bruker DPX 250 and a Bruker DRX 500 spectrometer , using the proton or carbon signal of the solvent as an internal standard. The thermolysis reactions were carried out in sealed quartz tubes in a temperature controlled electromagnetic oven. SEM measurements were(More)