A H Hoffman

Learn More
1. The sensitivity of group II joint afferents innervating cat knee joint capsule to in-plane stretch was studied in vitro. Single afferents were recorded from teased filaments of the posterior articular nerve. The capsule was stretched by applying forces through tabs along the edges of the capsule (3 tabs/edge) with the use of an apparatus that allowed for(More)
1. Experiments were conducted to test the hypothesis that the responses of joint capsule mechanoreceptors better encode tissue stress or tissue strain. The experimental model was a small ligament from the cat knee capsule, which was stretched uniaxially in vitro. Experiments were done with either force or displacement as the controlled variable, and with(More)
Mechanoreceptive afferents innervating the posterior capsule of the cat knee joint were recorded in a preparation of isolated capsule. The purpose of the experiments was to identify mechanical states in the capsule that were associated with afferent discharge. The capsule was excised from the knee with its bone attachments intact, so that the geometry of(More)
1. Experiments were performed to determine whether the response of stretch-sensitive mechanoreceptors to tissue deformation is caused by the axial stretching of the tissue or by the associated transverse compression of the tissue caused by the Poisson effect. 2. Single, stretch-sensitive mechanoreceptors were recorded in vitro in a preparation of(More)
A method has been developed whereby the discharge of mechanically sensitive neurons from the cat knee joint capsule can be calibrated and used as load cells. The neurons are located in the upper edge of the capsule which has been previously modeled as a suspension cable and where the loading has been shown to be one dimensional. The calibration procedure(More)
The vertical loading in the posterior capsule of the cat knee has been measured while the knee is rotated into hyperextension. Tissue loading was determined using a previously verified model of the capsule that represents its upper edge as a catenary suspension cable. Tensile loads in the cable were measured using the discharge of mechanoreceptive sensory(More)
  • Faculty R D Cheetham, J C Bagshaw, J E Miller, Case Western, P J Weathers, D S Adams +35 others
  • 2011
Programs of Study Students in the biology master's program learn to apply basic principles of the discipline to solving research problems, and broaden their knowledge of the subject through formal course offerings. Graduates with this degree may pursue further graduate education or choose to work in a research, clinical or industrial setting, applying their(More)
Deformation and loading of the knee posterior joint capsule were studied in the cat, in extension rotations and in axial external (ER) and internal (IR) rotations at full extension. Loads were measured in the ligament along the upper edge of the capsule, using mechanically sensitive neurons that were calibrated as load cells. Strains were measured across(More)