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A survey for West Nile Virus (WNV) haemagglutination-inhibition (HI) antibody was carried out in humans and domestic animals. Human sera were collected from Ibadan, while the animal sera were collected from both Ibadan and Maiduguri. Out of 304 human sera tested, 123 were positive (40%). There was a higher prevalence of HI antibody in adults than children.(More)
A study of Zika virus infections was carried out in four communities in Oyo State, Nigeria. Virus isolation studies between 1971 and 1975 yielded two virus isolations from human cases of mild febrile illness. Haemagglutination-inhibition tests revealed a high prevalence of antibodies to Zika and three other flaviviruses used. The percentages of positive(More)
A survey for haemagglutination-inhibiting arthropod-borne virus antibody was carried out in the Kainji Lake area of Nigeria. Of 267 persons tested, 139 (52%) and 158 (59%) had alphavirus and flavivirus group HI antibody, respectively. The prevalence of antibody to individual virus antigen is as follows: Chikungunya, 45%; Semliki Forest, 25%; Sindbis, 33%,(More)
  • A Fagbami
  • 1977
A study of arbovirus infections occurring in Igbo-Ora community was carried out between May and October 1975. Haemagglutination inhibition test performed on seventy-eight human sera showed a high prevalence of antibodies against all the six arboviruses used. Percentage of positive sera were as follows: Chikungunya, (28%); Yellow fever (36%); Dengue type 1(More)
Three primates inoculated with Congo virus (CV) developed viremia. The animals showed neither any rise in rectal temperature, nor signs of overt disease; however, in one of them pruritus and rash were observed. Skin biopsy revealed vasculitis and hemorrhage. By complement fixation, neutralization and gel diffusion tests CV antibodies were demonstrated in(More)
A community-based prospective study was carried out in the city of Ibadan, Nigeria, to determine the epidemiology of rotavirus infection and diarrhoea among children in the first two years of life. Implementation of the proposed study methods was hindered by a number of factors common to large urban areas in developing Africa. These factors included(More)
Two hundred and thirteen neonates from an urban and a rural community in Nigeria were examined for neonatal rotavirus infection. Twenty-four (11%) were shedding rotavirus in their stools. All newborns shedding rotavirus were either asymptomatic or had very mild diarrhoea. Most infections (71%) were detected during the first week of life; 21% and 8% occurred(More)
In a 30-month prospective study of severe acute lower respiratory infections in hospitalized pre-school Nigerian children, acute bronchiolitis was diagnosed in 67 cases; 19 (28.4%) and 2 (3.0%) of these had concomitant pneumonia or croup, respectively. The peak prevalence was in the wet (rainy) season (May-October). The male/female (M:F) ratio in infants <(More)
Cross-infection enhancement of seven African flaviviruses by subneutralising concentrations of antibody in immune ascitic fluids was investigated in P388D1 cell culture. Infection by all the seven flaviviruses tested was enhanced by homologous and at least one of six heterologous immune mouse ascitic fluids (IMAF) tested. Enhancement ratios and enhancing(More)