A. G. Matveenko

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Previously, we proposed a test system that allows one to search for genes that influence the properties of Sup35 and Sup45 proteins. This test is based on the phenomenon of the lethality of diploids that combine mutations in the SUP45 gene with [PSI +] prion. The lethality of this combination depends on both the type of sup45 mutation and the properties of(More)
Translation termination is an important step in gene expression. Its correct processing is governed by eRF1 (Sup45) and eRF3 (Sup35) proteins. In Saccharomyces cerevisiae, mutations in the corresponding genes, as well as Sup35 aggregation in [PSI +] cells that propagate the prion form of Sup35 lead to inaccurate stop codon recognition and, consequently,(More)
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