A. G. Khalmuradov

  • Citations Per Year
Learn More
Nicotinic acid and nicotinamide inhibit in vitro the acetyl-CoA-carboxylase activity of partially purified enzyme from chicken liver. The incorporation of 10, 20, 50 and 100 mkmoles of nicotinic acid or nicotinamide into the incubation medium (0,9 ml) leads to the inhibition of the enzyme activity by 19, 45, 70 and 100% and by 39, 51, 60 and 78%,(More)
The content of NAD and DNA, the activity of DNA-polymerase the velocity of NAD pyrophosphorolysis have been studied in liver nuclei of 8, 14, 18 day-old chicken embryos and 1--2 month- and 6 month-old chickens. It has been found that during ontogenesis the NAD content in chicken liver nuclei is increased, whereas the DNA content is decreased, the(More)
The paper deals with modern ideas concerning molecular mechanisms of the biosynthesis, metabolism and function of ascorbic acid as with as with its transport through the membrane structures of different extent of organization. It is emphasized that under physiological conditions a quickly saturated mechanism of ascorbic acid active transport through the(More)
Changes of acetyl-CoA-carboxylase (EC 6.4.1.2) activity and the NAD content in the liver tissue were studied in dynamics after excessive administration of nicotinic acid to chickens. It is established that in chickens, which were given a high-carbohydrate diet after fasting, administration of nicotinic acid at first causes a fall of the acetyl-CoA-activity(More)
Acetyl-CoA-carboxylase is isolated and purified to a homogeneous state from the chicken liver with alimentary lipogenesis stimulation. Under the action of nicotinic acid in vivo the specific enzyme activity is shown to decrease considerably followed by some variations in its properties. According to the results obtained during ultracentrifugation and PAAG(More)