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Journals and Conferences
The cusps formed by two barely overlapping nanoholes in a metal film enhance the local field and allow for order of magnitude surface-enhanced Raman over single holes.
The maximum wavelength at which light can propagate through a rectangular hole in a metal is dramatically increased due to the existence of surface-plasmon (SP) waves along the edges of the hole. For example, a 15-nm-wide hole in silver can have a cutoff wavelength more than double that of a perfect electric conductor. Furthermore, we show that there is a… (More)
Methods to insert, keep and fix silver and gold nanoparticles to the inner walls of microstructured fibers are demonstrated. Fibers optimized for evanescent field interaction were employed and can result in efficient plasmonic chemical sensing.
We demonstrate surface plasmon resonance (SPR) sensing based on the polarization dependence of extraordinary optical transmission through a biaxial nanohole array. This structure provides the benefit of having two nearly-degenerate periodicities in a single array that can be individually probed by varying polarization. This enables spectral diversity, even… (More)
Metallic nanostructures facilitate analyte sensing through localization of surface plasmons. In this work, we demonstrate that the same metal nanostructures can also facilitate the concentration and localization of analyte at the active sensing surface. Specifically, the structure of flow-through plasmonic nanohole array sensors presents the opportunity of… (More)
The coupling mechanism in surface-plasmon enhanced optical transmission through square lattice arrays of nanoholes was investigated by considering two different bases for the array: ellipses and double-holes. A comparison was made between the transmission properties of these bases, and for different orientations of each basis. The two cases showed similar… (More)
The cut-off wavelength of a rectangular waveguide in a metal is shown to increase dramatically as the hole is reduced in width. This effect is shown to result from surface-plasmon coupling within the hole.
A microfluidic device with an embedded surface-plasmon resonance (SPR) sensor array was developed. The sensing elements are nanohole arrays, differentiated by periodicity. On-chip chemical detection using SPR is demonstrated
Isolation of monoclonal (M-) antibodies (Abs) from Ab-secreting cells (ASCs) is impeded by difficulties in identifying the minority of ASCs secreting Ab(s) of interest. We present a novel label-free system that traps ASCs into biocompatible microwells and detects the binding of secreted Ab(s), to a surface-immobilized antigen (Ag), as induced shifts in the… (More)
Polarization dependent SPR-based sensing is demonstrated using a biaxial nanohole array. This enables increased spectral diversity and sensitivity with single line excitation. Towards further optofluidic integration, a flow- through array detection scheme is evaluated computationally.