A. G. Brito-Madurro

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Anaplasmosis, a persistent intraerythrocytic infection of cattle by Anaplasma marginale, causes severe anemia and a higher rate of abortion, resulting in significant loss to both dairy and beef industries. Clinical diagnosis is based on symptoms and confirmatory laboratory tests are required. Currently, all the diagnostic assays have been developed with(More)
This work describes the immobilization of purine and pyrimidine bases and immobilization/hybridization of synthetic oligonucleotides on graphite electrodes modified with poly(4-methoxyphenethylamine) produced in acid medium. The immobilization of adenine, guanine, cytosine and thymine on these modified electrodes was efficient, producing characteristic(More)
Background Hepatitis B is an infectious disease of the liver, highly prevalent in society, caused by hepadnavirus (HBV), which affects approximately 350 million individuals worldwide [1]. It is estimated that the number of deaths from the disease is in the range of 2000 to 4000 per year, mainly by hepatic cirrhosis and hepatocellular carcinoma [2]. Due to(More)
Introduction The current frontiers in biological sciences demand an interface among disciplines of biology, chemistry, and physics to achieve new paradigms in applied nanobio-technologies to health. opening new possibilities for biological manipulations aiming improved diagnostics and therapeutics. New rationale is required to use available technologies(More)
This paper describes methodology for direct and indirect detections of a specific oligonucleotide for Epstein-Barr virus (EBV) using electrochemical techniques. The sequence of oligonucleotide probe (EBV1) revealed a high sequence identity (100%) with the EBV genome. For the development of the genosensor, EBV1 was grafted to the platform sensitized with(More)
Background The C-reactive protein (CRP or PTX1) is an acute phase protein, expressed by hepatocytes, that is regarded as a clinical marker for infection and has been increasingly used as a risk indicator in chronic inflammatory diseases [1]. Atherosclerosis is an inflammatory disease that remains a major cause of morbidity and mortality. Its progression is(More)
ZnO nanocrystals were successfully fabricated by wet-chemical method. Optical properties of excitons confined in ZnO nanocrystals were studied by measuring both optical absorption and photoluminescence spectra. Absorption due to free excitons was clearly observed whereas strong PL lines were recorded in the UV region at around the exciton absorption energy.(More)
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