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Various methods have been proposed to calculate a lateralization index (LI) on the basis of functional magnetic resonance imaging (fMRI) data. Most of them are either based on the extent of the activated brain region (i.e., the number of "active" voxels) or the magnitude of the fMRI signal change. The purpose of the present study was to investigate the(More)
In functional imaging of the brain, the difficulty of a task may be critical for the pattern of activation. Increased task difficulty could lead to increased activation in task-specific regions or to activation of additional, "compensatory" regions. A previous study with functional transcranial Doppler sonography (fTCD) showed no evidence that increased(More)
We examined the influence of rapid-rate transcranial magnetic stimulation on heart rate and blood pressure in 13 healthy volunteers. In a first series three different cortical magnetic stimuli were applied: over C3, C4 and Fz (10/20 system), in a second series additionally over Pz. We also used a stimulus over the brachial plexus and a sham stimulus. Five(More)
BACKGROUND A high proportion of patients with essential hypertension need a combination therapy to reach the therapeutic goal. In the present study, the tolerability and efficacy of a fixed, once daily combination of the AT1 blocker Losartan (100 mg) and the diuretic hydrochlorothiazide (HCTZ) (25 mg) for patients in the real-life situation was(More)
Complaints of angina pectoris after aortocoronary bypass surgery can be due to the obturation of one or more bypasses. The aim of our study was the evaluation of magnetic resonance tomography for the investigation of bypass patency in comparison with computed tomography. We investigated 18 patients. 33 of 35 bypasses were safely detectable with spin-echo(More)
Tay-Sachs disease is caused by Hexosaminidase A deficiency. Symptoms of the enzyme deficiency rarely become clinically manifest in adult age; then the course of the disease differs in a wide range. We report on a patient with cerebellar ataxia and lower motor neuron disease. Neurophysiological investigations, neuro-imaging (CT, MRI), and muscle biopsy(More)
Besides painful ophthalmoplegia, patients suffering from Tolosa-Hunt syndrome often present increasing loss of visual perception. The impairment of the optic nerve leads to a delay of the VEP (visual evoked potentials) responses. Using the method of magnetic resonance imaging (MRI), some patients present unspecific alterations in the vicinity of the optic(More)
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