A E Sahr

Learn More
BACKGROUND This study tested the hypothesis that ethanol consumption by alcohol-preferring (P) rats during the periadolescent period causes persistent alterations in the mesolimbic dopamine (DA) system. After ethanol drinking during periadolescence, P rats were examined for alterations in basal locomotor activity, changes in extracellular DA levels and(More)
An analog of the 3,4-dimethyl-4-(3-hydroxyphenyl)piperidine series, LY255582, exhibits high in vitro binding affinity and antagonist potency for the opioid receptors: mu, delta, and kappa. In vivo, LY255582 exhibits potent effects in reducing food intake and body weight in several rodent models of obesity. In the present study we evaluated the effects of(More)
  • 1