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Developmental changes in diffusion anisotropy coincide with immature oligodendrocyte progression and maturation of compound action potential.

• A Drobyshevsky, Sheng-Kwei Song, +10 authors Sidhartha Tan
• The Journal of neuroscience : the official…
• 2005

Disruption of oligodendrocyte lineage progression is implicated in the white-matter injury that occurs in cerebral palsy. We have previously published a model in rabbits consistent with cerebral… (More)

Serial diffusion tensor imaging detects white matter changes that correlate with motor outcome in premature infants.

• A Drobyshevsky, Joanne C Bregman, +5 authors Sidhartha Tan
• Developmental neuroscience
• 2007

The objective of the study was to assess predictive value of serial diffusion tensor MRI (DTI) for the white matter injury and neurodevelopmental outcome in a cohort of premature infants. Twenty-four… (More)

Structure of chemical compounds, methods of analysis and process control

• Nikolay Alekseev, A Drobyshevsky, D. A. Rozhdestvensky
• Pharmaceutical Chemistry Journal
• 2011

A procedure for the rapid determination of nimesulide (N) and its active metabolite (M1) [4′-nitro-2′-(4-hydroxyphenyloxyphenyl)methanesulfonamide] in human serum that includes solid-phase extraction… (More)

A rapid fMRI task battery for mapping of visual, motor, cognitive, and emotional function

• A Drobyshevsky, Stephen Baumann, Walter Schneider
• NeuroImage
• 2006

A set of sensory, motor, cognitive, and emotional tasks were combined in a simple, rapid-presentation task battery and tested on a group of 31, normal, healthy subjects aged 22 to 76. Five tasks were… (More)

Human Umbilical Cord Blood Cells Ameliorate Motor Deficits in Rabbits in a Cerebral Palsy Model.

• A Drobyshevsky, Charles Michael Cotten, +8 authors Sidhartha Tan
• Developmental neuroscience
• 2015

Cerebral palsy (CP) has a significant impact on both patients and society, but therapy is limited. Human umbilical cord blood cells (HUCBC), containing various stem and progenitor cells, have been… (More)

Motor deficits are triggered by reperfusion-reoxygenation injury as diagnosed by MRI and by a mechanism involving oxidants.

• A Drobyshevsky, Kehuan Luo, +6 authors Sidhartha Tan
• The Journal of neuroscience : the official…
• 2012

The early antecedents of cerebral palsy (CP) are unknown but are suspected to be due to hypoxia-ischemia (H-I). In our rabbit model of CP, the MRI biomarker, apparent diffusion coefficient (ADC) on… (More)

Model of cerebral palsy in the perinatal rabbit.

• Sidhartha Tan, A Drobyshevsky, +4 authors M Elizabeth Derrick
• Journal of child neurology
• 2005

Perinatal brain injury results in one of the highest burdens of disease in view of the lifelong consequences and is of enormous cost to society. This makes it imperative to develop better animal… (More)

Fetal brain magnetic resonance imaging response acutely to hypoxia-ischemia predicts postnatal outcome.

• A Drobyshevsky, M Elizabeth Derrick, Pottumarthi Vara Prasad, Xinhai Ji, Ila Englof, Sidhartha Tan
• Annals of neurology
• 2007

OBJECTIVE Cerebral palsy (CP) is caused by either hypoxia-ischemia (H-I) or long-standing causative factors such as inflammation or genetics. Multiple pathophysiological events over time are thought… (More)

Unmyelinated axon loss with postnatal hypertonia after fetal hypoxia.

• A Drobyshevsky, Rugang Jiang, +4 authors Sidhartha Tan
• Annals of neurology
• 2014

OBJECTIVE White matter (WM) injury due to myelination defects is believed to be responsible for the motor deficits seen in cerebral palsy. We tested the hypothesis that the predominant injury is to… (More)

Sensory deficits and olfactory system injury detected by novel application of MEMRI in newborn rabbit after antenatal hypoxia–ischemia

• A Drobyshevsky, Alan M. Robinson, +4 authors Sidhartha Tan
• NeuroImage
• 2006

Sensory deficits are frequently observed in cerebral palsy patients. The motor response to smell was found to be abnormal in an animal model of cerebral palsy following fetal hypoxia-ischemia. We… (More)

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