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[Respiration and oxidative phosphorylation in isolated liver cells under freezing conditions].
Respiration and oxidative phosphorylation of hepatocytes were studied as affected by low temperatures and cryoprotectors. Fast freezing of these cells down to -196 degrees C with the presence ofExpand
[The effect of altan on the functional activity of the liver mitochondria and microsomes from rats with toxic hepatitis].
In in vitro experiments althan had no effect on the respiration of intact mitochondria in state 4 according to Chance and produced a high antioxidant effect in fermentative and ascorbate-dependentExpand
[Hepatoprotective effect of lipophen--a novel natural combined phospholipid preparation].
  • A D Gordienko
  • Medicine
  • Eksperimental'naia i klinicheskaia farmakologiia
  • 2001
Studied in vitro, lipophen (in contrast to essentiale) did not separate the oxidation and phosphorylation processes in intact mitochondria. The antioxidant effect of lipophen with respect toExpand
[The pharmacologic and biochemical effects of unsaturated phospholipids].
The review deals with the analysis of the recent publications indicating the important biological function of essential phospholopids (EP) in the cell and in the organism as a whole. The protectiveExpand
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[Pharmacokinetics of lipophen--a novel combined phospholipid liver protective agent of natural origin].
Study of the labeled lipophen distribution in organs and tissues of experimental animals showed evidence of a nonlinear drug pharmacokinetics. The maximum amount of labeled lipophen accumulated inExpand
[ATP, ADP and AMP content in the low-temperature preservation of lymphoid cells].
As compared with ATP and ADP concentration in native lymphocytes, content of ATP was decreased down to 26.3% and 35.1% and of ADP--37.0% and 44.4% in the cell preparations after conservation inExpand
  • 1
[Respiration activity of frozen-thawed lymphoid cells].
The respiration and oxidative phosphorylation rate of lymphocytes were studied after their cryopreservation. The oxygen uptake of cells frozen in the freezing medium containing 20% serum and 10%Expand
[Effect on freezing on hydroxylation in isolated hepatocytes].
Rapid freezing of hepatocytes down to--196 degrees was accompanied by a distinct impairment in microsomal oxidation and by complete uncoupling of respiration and oxidative phosphorylation inExpand
[The effect of hepatoprotectors on the functional activity of rat hepatocyte mitochondria in in-vitro and in-vivo systems].
  • A D Gordienko
  • Medicine
  • Eksperimental'naia i klinicheskaia farmakologiia
  • 1992
In in vitro experiments essential, flacumin, and silibor inhibited the respiratory activity of isolated mitochondria and failed to affect the respiration of hepatocytes in rats at condition 4 byExpand
[Glycolysis in native and cryopreserved lymphocytes].