A D Collins

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PURPOSE To study the effect of monocular visual deprivation caused by dense unilateral cataracts in adults. METHODS Visual evoked potentials have been recorded in 11 patients after removal of a dense unilateral cataract acquired in adulthood. These were compared with those from 8 control patients after removal of a mild lens opacity. RESULTS Visual(More)
PURPOSE To study the maturation of normal binocular vision. METHODS Binocular visual function has been studied and monocular and binocular pattern reversal visual-evoked potentials (VEP) recorded in 20 normal subjects aged 5 to 43 years. RESULTS Stereoacuity improved significantly between the age of 5 and adulthood. Mean stereoacuity for eight children(More)
PURPOSE To perform an electrophysiological study of central areolar choroidal dystrophy (CACD) in the affected members of a four generation family. METHODS Eight affected family members from the last three generations of a family affected by CACD were assessed by full-field electroretinograms (rod response, maximal combined response, oscillatory(More)
The investigation of patients who are unable to fixate the pattern visual stimulus generally requires the use of diffuse flash stimulation to elicit the visual evoked response. However, by comparison with pattern, flash stimulation has proved relatively insensitive in identifying lesions of the visual pathway. We investigated a more complex method of flash(More)
PURPOSE To study the effects of Duane's retraction syndrome on sensory visual development. METHODS Monocular and binocular visual function and ocular motility have been studied and pattern reversal visual evoked potentials recorded from 22 patients with Duane's syndrome aged from 4 to 55 years. RESULTS Sixteen of the patients maintained binocular single(More)
We applied a complex segregation analysis to 46 pedigrees with a total of 121 nuclear families and 660 individuals, to verify hypotheses regarding the inheritance of OFC and linkage with markers on chromosomes 6 and 2. The POINTER program for segregation analysis strongly rejected the hypothesis of no familial transmission of OFC in these families. When the(More)
  • J Appl Physiol, P Harris, A D Collins, Birmingham Wright, Research C H E Medical, S D Imray +20 others
  • 2008
humans Effect of acute severe hypoxia on peripheral fatigue and endurance capacity in healthy Cerebral blood flow and metabolism during exercise: implications for fatigue including high-resolution figures, can be found at: Updated information and services those papers emphasizing adaptive and integrative mechanisms. It is published 12 times a year (monthly)(More)
Monocular and binocular visual evoked potentials were recorded in eight patients with Duane's syndrome who used an abnormal head posture to maintain binocular single vision. With their abnormal head posture, all patients had stereoscopic vision, although with mildly reduced stereoacuity, and the visual evoked potential showed binocular enhancement (mean(More)
A 17-year-old male suffered superficial and deep facial burns after coming into contact with a high tension electrical cable with his head and right side of the face. The right eye sustained severe thermal coagulative injuries and subsequently was enucleated. Histopathological examination showed that the retinal neuropile was relatively intact although the(More)
When recording pattern visual evoked potentials it is important that the overall luminance of the pattern and the relative luminance of the pattern elements (for example checks or bars) are maintained at a constant level. This paper describes a low-cost battery-powered instrument designed and constructed to measure the luminance of specific areas of the(More)