A Compagnone

Learn More
Histone deacetylase inhibitors (HDIs) are valuable drugs in breast cancer where estrogen receptor alpha (ER alpha) can be silenced by epigenetic modifications. We report the effect of the clinically available HDI, valproic acid (VPA), on ER alpha expression and function in ER-negative breast cancer cells, MDA-MB-231. VPA induced ER alpha mRNA and protein,(More)
We report a boy, who achieved developmental milestones without delay, presenting complex partial seizures (left-deviation of the head, staring gaze, oral automatism and tonic-clonic generalization) at 7 years: his blood/cerebro-spinal fluid tests were all within normal limits, enclosed those for inborn errors of metabolism. Progressive signs of psycho-motor(More)
  • 1