A. Cafarelli

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In the last century, medicine showed considerable advancements in terms of new technologies, devices and diagnostic/therapeutic strategies. Those advantages led to a significant reduction of invasiveness and an improvement of surgical outcomes. In this framework, a computer-assisted surgical robotic platform able to perform non-invasive Focused Ultrasound(More)
Described here is an in vitro systematic investigation of the effects on C2C12 myoblasts of exposure to finely controlled and repeatable low-intensity pulsed ultrasound of different frequencies (500 kHz, 1 MHz, 3 MHz and 5 MHz) and different intensities (250, 500 and 1000 mW/cm2). An in-house stimulation system and an ultrasound-transparent cell culture(More)
Materials with tailored acoustic properties are of great interest for both the development of tissue-mimicking phantoms for ultrasound tests and smart scaffolds for ultrasound mediated tissue engineering and regenerative medicine. In this study, we assessed the acoustic properties (speed of sound, acoustic impedance and attenuation coefficient) of three(More)
PURPOSE In this work we provide measurements of speed of sound (SoS) and acoustic impedance (Z) of some doped/non-doped rubber-based materials dedicated to the development of ultrasound phantoms. These data are expected to be useful for speeding-up the preparation of multi-organ phantoms which show similar echogenicity to real tissues. METHODS Different(More)
Objectives Thalamotomy of the ventral intermediate nucleus (VIM) is effective in alleviating medication resistant tremor in patients with essential tremor (ET) and Parkinson's disease (PD). MRI guided Focused Ultra-sound (MRgFUS) is an innovative technology that enables non-invasive thalamotomy via thermal ablation. Methods Thirty eight ET and PD patients(More)
Background Being cardiovascular diseases the leading cause of death worldwide, a prompt intervention is needed to restore blood flow. Sonothrombolysis with/without addiction of thrombolytic drugs is explored as a promising solution, thanks to its non-invasiveness, precision and action quickness. Even if the involved mechanisms are not completely understood,(More)
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