A. Brahma Reddy

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Clarithromycin (CM), a broad spectrum macrolide antibiotic used to eradicate H. pylori in peptic ulcer. Clarithromycin (CM) is well absorbed from the gastrointestinal tract, but has a bioavailability of 50% due to rapid biodegradation. The aim of this investigation was to increase the gastric residence time, and to control the drug release of clarithromycin(More)
The aim of the present investigation is to formulate and evaluate Tizanidine hydrochloride sustained release pellets. Tizanidine hydrochloride is an immadazole α2-adrenergic agonist used in the management of increase in muscle tone associated with spasticity. It has short biological half-life of 22.5 hrs and is rapidly eliminated from the body. Sustained(More)
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