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A novel microelectronic "pill" has been developed for in situ studies of the gastro-intestinal tract, combining microsensors and integrated circuits with system-level integration technology. The measurement parameters include real-time remote recording of temperature, pH, conductivity, and dissolved oxygen. The unit comprises an outer biocompatible capsule(More)
There is considerable interest in the development of ultra-miniature and low-power sensor microsystems for use in applications such as medical diagnostics, environmental monitoring and other industrial applications. Such ultra-miniature sensor microsystems must contain a large diversity of complex electronics, including sensor interfaces, signal(More)
This paper presents an analysis of the noise propagated across the substrate and the electromagnetic contamination in a control chip for a wireless Lab-in-a-Pill. This chip integrates analogue, digital and radio frequency circuits monolithically to reduce the physical size, power consumption and packaging cost of the capsule. Several approaches to minimise(More)
The introduction of microsystem technology into diagnostic devices is a rapidly growing field where low form-factor can significantly improve device access or patient comfort. In this paper we will present our results on a lab-in-a-pill device that uses laboratory-on-a-chip and system-on-chip technology to deliver analytical data from a range of sensors,(More)
A state-of-the-art electronic " pill " has been developed for in situ studies of the gastro-intestinal (GI) tract using integrated circuit and system level integration technologies. The measurement parameters include real time analysis of temperature, pH, conductivity and dissolved oxygen. 1. Introduction Ingestible analytical microsystems have extended the(More)
Clinical advantages have led to the continuous exploitation of a series of wireless lab-in-a-pill (LIAP) devices for gastroenterology diagnostics [1-3]. Such a LIAP can be swallowed into a patient's gastrointestinal tract with relative ease, and then transported from the mouth to the anus by natural peristalsis. There is now a great deal of interest in(More)
encoder and a frequency shift keying (FSK) RF transmitter. Many of the system blocks are from pre-Recent years have seen the rapid development of existing libraries, or have been written and imported in an microsensor technology, system on chip design, wireless intellectual property (IP) block form, thus the design technology and ubiquitous computing. When(More)
I Abstract-Developments in system-on<hip and wireless technologies have led to complex electronic systems to he miniaturized to size of ingestible capsule and implantable microsystems. Inevitably such miniaturized complex systems impose some constraints on the case of an ingestible diagnostic capsule. It is desirable that system be wireless, programmable,(More)
We have developed an integrated circuit microsystem instrument using a design methodology akin to that for system-on-chip microelectronics. The microsystem is optimised for low-power gastrointestinal telemetry applications and includes mixed-signal sensor circuits, programmable digital system, a feedback clock control loop and RF circuits that were(More)