Learn More
We describe a 47-year-old patient with chronic anaemia with basophilic stippling of erythrocytes, recurrent abdominal colics, discoloration of gums, sensitive polyneuropathy to the four limbs, hyperuricaemia, hepatosteatosis with raised transaminases, and a long ignored history of lead exposure in a battery recycling plant. The diagnosis of poisoning was(More)
Since recombinant growth hormone (GH) has been available, its use has been extended to treating not only children with growth hormone deficiency, but also short-statured children without GH deficiency. It is interesting, therefore, to determine whether GH therapy given in conventional doses causes metabolic side effects in these patients. In the present(More)
The effects of caerulein and some related substances were investigated on the sphincter of Oddi which had been contracted by morphine in the guinea-pig, and on the isolated terminal bile duct in the calf. In the first test caerulein (50–100 ng/kg i.v.) was the most potent spasmolytic drug whereas in the second test the peptide (0.75-1 Μg/ml) produced(More)
The effects of cimetidine and ranitidine, alone or combined with sulglycotide or carbenoxolone, and those of 16,16-dimethyl prostaglandin E2 were investigated on mucosal lesions induced in pylorus-ligated rats. The drugs were administered orally after pylorus ligation; 3 hr later the animals were killed, the stomachs removed and examined for the presence of(More)
Simvastatin is an effective hypocholesterolemic drug that inhibits cholesterol synthesis selectively in the liver, but could have potential side effects on the adrenal gland, ovary, and testis, as these three glands use cholesterol for their hormonal biosynthesis. In this report, we examined adrenal and sex steroids in 10 type IIA hypercholesterolemic(More)
The authors analyse the method used between 1983 and 1990 in 161 patients with chronic anterior laxity of the knee treated by 162 ligament reconstructions utilizing synthetic ligament prostheses. Tearing of the prosthetic ligament is the most feared and frequent complication. This may be due to technical error, wear of the material or, to a lesser extent,(More)
Arthroscopic surgery is generally considered to be free of any significant complications. In particular, there is a much lower incidence of vascular complications as compared with open surgery of the knee. A careful examination of the literature, made by the authors, and an in-depth analysis of a significant sample (790 patients over 2 years) out of a total(More)