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BACKGROUND High-protein diets promote weight loss and subsequent weight maintenance, but are difficult to adhere to. The mechanisms by which protein exerts these effects remain unclear. However, the amino acids produced by protein digestion may have a role in driving protein-induced satiety. METHODS We tested the effects of a range of amino acids on food(More)
Obesity is a leading cause of morbidity and mortality worldwide. There is still a wide disparity between the necessity and availability of safe and effective antiobesity pharmacotherapies. Current drugs are associated with adverse effects and are limited in their efficacy. There is thus an urgent need for new antiobesity agents. Animal models are critical(More)
This paper studies the modified sensitivity analysis applied into an elastic-plastic finite element analysis of a 3D blank design in sheet metal forming. Originally the sensitivity method has successfully been applied to several arbitrary shapes. In the present paper the sensitivity coefficients are not considered constant during the analysis. The presented(More)
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