A. A. Tsegel'skii

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The carbohydrate determinants of the cell surface of neuroblastoma C 1300 clone N 18 have been investigated by light microscopy with a panel of 11 lectins as cytochemical reagents. The expression of N- and O-glycanes with a predominance of 3-4 antigenic N-glycosyl chains was revealed. The characteristic feature of neuroblastoma cells is an abundance of an(More)
Different phosphate concentrations were studied for their effect on the degradation of adenosine by rat liver homogenates. It is shown that phosphate considerably inhibits the phosphoribomutase reaction without a significant effect on adenosine deaminase and purine nucleoside phosphorylase activities, that leads to the ribose-1-phosphate accumulation and to(More)
The alkylation of uracil and methyluracil with thiophosphamide or benzotef was carried out in an aqueous medium at pH i0.0, and of nitrouracil in a neutral medium. The ethyleneimine rings of the reagent were opened, and the N-phosphorylated 2-aminoethyl residue entered into the 3-position of the uracil ring to form the corresponding derivatives. Thus,(More)
The interrelationship of NAD and adenosine (inosine) conversions in the rat liver is investigated. The ratio of products of NAD+ conversions (ADP-ribose, inosine, hypoxanthine and ribose phosphates) are established. AMP and adenosine are not detected, which indicates an availability of different activities of the corresponding enzymes. It is shown that(More)
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