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BACKGROUND Osteoporosis poses a significant public health issue. It is a skeletal disorder characterized by compromised bone strength that predisposes to increased risk of fracture. There is a direct relationship between the lack of estrogen after menopause and the development of osteoporosis. About 33% of women over 50 will experience bone fractures as a(More)
Myocardial ischemia–reperfusion (I/R) represents a clinically relevant problem associated with thrombolysis, angioplasty, and coronary bypass surgery. Radical oxygen species generated during early reperfusion are the primary activator of mitochondrial permeability transition pore (MPTP) opening which finally results in cardiomyocyte death. Nigella sativa(More)
Vitamin D, most commonly associated with the growth and remodeling of bone, has been shown to ameliorate ischemia/reperfusion injury (IRI) in some tissues, yet its underlying mechanism remains elusive. This study was designed to examine the protective effect of vitamin D, if any, against hepatic IRI in rats and the underlying mechanism involved. Adult(More)
  • A A Seif
  • 2015
BACKGROUND Hypercholesterolemia indirectly increases the risk of myocardial infarction by enhancing platelet aggregation. Chromium has been shown to lower plasma lipids. AIM This study was designed to investigate whether chromium inhibits platelet aggregation under hypercholesterolemic conditions. METHODS Albino rats were divided into four groups:(More)
BACKGROUND AND AIMS Although the beneficial effects of exercise on fatty liver have been described, a previous study conducted at our department showed that transcutaneous electrical muscle stimulation (TEMS) of lower abdominal muscles aggravated fatty liver. The present study aims to evaluate the ability of TEMS of the lower limb muscles to improve fatty(More)
AIM To evaluate the possible beneficial effect of long-term caffeine administration on cardiovascular system in aged rats. METHODS This study was carried out on 20 senile male albino rats, aged 18-20 months. Rats were divided into caffeine-treated group, which received 25 mg/kg caffeine by gavage daily for 6 weeks, and control group. All rats were(More)
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