A. A. Pinevich

  • Citations Per Year
Learn More
Endoglin (CD105), a component of TGF-β, BMP-9, BMP-10 binding receptor complexes, is the marker of endothelial and mesenchymal stem cells. Its expression is significantly increased in the blood vessel endothelium of ischemic tissues and growing tumors. Measurement of the endoglin soluble form in serum and urine is used in diagnostics of cancer and pregnancy(More)
Mesenchymal stromal cells were isolated from the adipose tissue obtained during surgery for breast cancer and cultured under conditions of normal or low oxygen concentrations. In patients that had received a course of radiation and polychemotherapy prior to surgery, the proliferative potential of mesenchymal stromal cells was irreversibly disturbed. In(More)
There are conflicting data on the influence of mesenchymal stromal cells (MSCs) on B-lymphocyte growth, differentiation, and immunoglobulin (Ig) production. The aim of this study was to investigate the influence of MSCs derived from the adipose tissue of healthy donors and cancer patients on the proliferation and Ig synthesis of the lymphoblastoid cell line(More)
The data concerning the influence of mesenchymal stromal cells (MSCs) on immunoglobulin (Ig) production are contradictory. Most results were obtained using MSC derived from bone marrow. The properties of MSCs obtained from other tissues are not well studied. In the present work, MSC cultures have been established from umbilical cord, adipose tissue, and(More)
Evolutionary conservative and species-specific epitopes of thyroglobulins (Tg) from different mammalian species were studied using panel of 20 monoclonal antibodies (mAb) raised in our laboratory and recognizing 16 antigen determinants on human Tg molecule. Cross-reactivity of mAb with preparations of purified mammalian Tg from other species was studied by(More)
Endoglin (CD105) is the marker of endothelial and mesenchymal stem cells and the component of TGF-β, BMP-9 and BMP-10-binding receptor complexes. Its expression is significantly increased on blood vessels endothelium of ischemic tissues and growing tumors. Measurement of concentration of the soluble endoglin in the serum or urine is used as a method for(More)
During prolonged cultivation, cell lines may lose a number of innate characteristics or acquire new ones. In this work, we compared growth and phenotypic characteristics of human glioblastoma А172 and Т98G cell lines received from the cell culture collection of the Research Institute of Influenza (St. Petersburg, Russia). The activity of genes encoding(More)
  • 1