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通过将单次单因子法和响应面法相结合的方法,对红曲霉菌株Monascus purpureus WX液态发酵产Monacolin K的工艺条件进行了优化.其较佳的工艺条件为:甘油102.2g/L,黄豆粉29.2g/L,NaNO3 2.0g/L,MgSO4·7H20 1.0g/L,KH2PO4 1.0g/L,初始pH4.5,26℃下培养15d.在此条件下,Monacolin(More)