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乙双吗啉(AT-1727)对小鼠L_(1210)细胞周期的影响
乙双吗啉(AT-1727)系任云峰等合成的一种抗肿瘤新药。实验证明它具有广谱抗肿瘤作用,放疗增效及选择性免疫抑制等作用,毒性较小。临床证明它对恶性淋巴瘤等有一定疗效。我组用放射自显影法研究表明乙双吗啉对S_(180)细胞的S、G_2、M期细胞均有一定作用,对G_0期细胞则无影响。用显微分光光度术研究发现它可引起L_(1210)的G_2期细胞堆积。
STUDIES ON RUBESCENSINE B: A NEW ANTITUMOR PRINCIPLE ISOLATED FROM DONGLINCAO
A Chinese herb called Donglincao was identified as Rabdosia rubescens (Hemsl) Hara (Labiatae). It is widely distributed in the Yellow River valley and used in folk medicine for the treatment ofExpand