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Studies on Structure-Activity Relationship of Nonquaternary AChE Reactivators
A series of dialkylaminoalkyl thioesters of α-keto thiohydroximic acid (4-RC_6H_4-COC·(NOH)-S-(CH_2)_n-NR′R″) as acetylcholinesterase (ACHE) reactivators in vitro were reported, whose correlationsExpand
STUDIES ON THE RELATIONSHIP BETWEEN THE MO REACTIVITY INDICES AND REVERSIBLE ANTICHOLINESTERASE ACTIVITY OF CUIXINGNING
Reversible anticholinesterase (anti-ChE)agents can inhibit the function of acetylcholinesterase (AChE)temporarily and have been used in the treatment of glaucoma and myasthenia gravis, and recentlyExpand
STUDIES ON THE CONFORMATIONS OF SUBEROGORGIN AND ITS METHYL ESTER BY MNDO METHOD
The novel reversible anticholinesterase (anti-ChE) agent suberogorgin (S) has potent anti-ChE activity and lower toxicity and is possible to become the new drug for the treatment of senile dementiaExpand