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APPLICATIONOFHMB-45MONOCLONALANTIBODYANDS100PROTEININTHEIMMUNOHISTOCHEMICALDIAGNOSISOFMELANOMALiuDanya(刘丹亚);SuBaoshan(苏宝山);Xu...
用EGF-R、PCNA及P53抗体和LBSA方法观察了43例寻常性银屑病患者表皮及12例正常皮肤。结果发现EGF-R及PCNA表达明显增强,除基底层细胞外,棘层及颗粒层也有明显表达,个别病例角度层仍有少量表达。提示银屑病患者皮损处细胞增殖及分化调控紊乱。还发现银屑病患者皮损及皮损周未受累皮肤中无P53的表达。