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Antibodies that specifically bind to Epha2 receptor
An antibody or epitope-binding fragment that specifically binds to EphA2 receptor and a method of preparing the conjugate and such conjugates comprise a cytotoxic agent covalently bound to the antibody.
Pyrrolo as anticancer agents [1,4] Conjugates of benzodiazepine dimer
The present invention relates to novel conjugates of pyrrolo that can be used as an anticancer agent [1,4] benzodiazepine dimer (I).
Process for the preparation of taxane derivatives
(57) Abstract: The protected baccatin III or 10-deacetylbaccatin III is esterified with the acid of formula (VII), the protective group elimination, by acylating the amine functional group of the…
Preparation of β- phenylisoserine and its analogues
Preparation of taxane derivatives, new derivatives are prepared, and pharmaceutical compositions comprising them
New farnesyl transferase inhibitors, pharmaceutical compositions containing their preparation and the inhibitor
(57) Abstract: A new farnesyl transferase inhibitors of general formula (I), their preparation, and pharmaceutical compositions comprising the inhibitors are disclosed. In the general formula (I), R
Novel taxoids, their preparation and pharmaceutical compositions containing them
Z novel products of general formula is a group of the general formula (II) (I) is significant anti - having leukemic - tumor and anti.
Pyrrolo [1,4] benzodiazepine dimer conjugates as anticancer agents
New process for the preparation of taxane derivatives, thus obtained novel derivatives and compositions containing them
A pharmaceutical composition comprising a novel derivative obtained for the preparation of taxane derivatives having the formula (I) has remarkable antitumor and antileukemic properties.
New therapeutic use cytotoxic agents and their containing tomaymycin derivative