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EFFICIENCY OF RECOMBINANT TNF-BINDING PROTEIN FROM VARIOLA VIRUS IN A MODEL OF COLLAGEN-INDUCED ARTHRITIS
Abstract. This paper presents the results of the research on the effectiveness of recombinant TNF-binding protein of variola virus (VARV-CrmB) in a model of collagen-induced arthritis (CIA) in miceExpand
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Интерлейкин-18 и его роль в иммунном ответе
Abstract. Interleukin–18 is one of the main cytokines, inducing production of IFNg. It is the important factor of anti–infectious and anti–tumor immunity. The review represent molecular–genetic andExpand
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БИОЛОГИЧЕСКИЕ ЭФФЕКТЫ РЕКОМБИНАНТНОГО БЕЛКА ВИРУСА НАТУРАЛЬНОЙ ОСПЫ, СВЯЗЫВАЮЩЕГО ФАКТОР НЕКРОЗА ОПУХОЛЕЙ
Abstract. This review presents a summary of our data concerning in vivo and in vitro effects of recombinant TNF-binding protein from variola virus (VARVCrmB) upon TNF-induced functional changes ofExpand
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Экспрессия мембранных рецепторов к фактору некроза опухоли у больных активным туберкулезом легких
Tumor necrosis factor (TNF) is a key cytokine in the immune response against Mycobacterium tuberculosis (M. tuberculosis). TNF can exhibit its biological eff ects in the presence of a suffi cientExpand
Method for isolating autoantibodies of immunoglobulin g subclasses to immunoregulatory cytokine tumor necrosis factor
FIELD: medicine. SUBSTANCE: invention relates to medicine and concerns a method for isolating subclasses of immunoglobulin G (IgG) autoantibodies against immunoregulatory cytokine tumor necrosisExpand
Получение рекомбинантного интерлейкина-18 и изучение его противоопухолевой активности
In present work are submitted the data on preparation of recombinant human interleukin-18 in E. coli cells, research by its biological activity in vitro and antitumoral activity in vivo. Is shown,Expand
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