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The concentration of bortezomib in patients with multiple myeloma by method of liquid chromatography with mass spectrometric detection after a single i/o bolus injection at a dose of 3,5 mg via(More)
Under experimental myocardial ischemia in rats of 10 months treatment with mildronate resulted in essential changes in metabolism of cardiomyocites. This includes stimulation of aerobic and anaerobic(More)
The review summarizes the results of clinical trials that identified galectin-3 as a biomarker of chronic heart failure. The article also describes experimental studies in vitro and in vivo for(More)
A simple, specific, sensitive and reproducible assay has been developed for the qualitative determination of piracetam and fenotropil in parent substances, dosage forms, and blood plasma using a(More)
Antifungal drugs are often applied in clinical practice because of high prevalence of fungoid infections. Antifungal drugs metabolize by system of biotransformation and transporters, and also can(More)
The slow calcium channels blockers are substrats of genetically polymorphic transporter glycoproteina-P. We was studied association caring genotypes on marker С3435Т of gene MDR1 and development(More)
Рассмотрены важнейшие биофармацевтические свойства, оказывающие влияние на достижение лекарственных веществ системного кровотока. Описаны такие свойства как биофармацевтическая растворимость,(More)
On the basis of given literatures, and also results of own researches are stated modern representations about system of biotransformation and drugs transporters, and also about the factors(More)
At present, Russia has developed domestic analogue of Memantine Akatinol — Memaneyrin in the form of droplets which is pharmaceutically equivalent drug memantine Akatinol. The aim of this study was(More)