Özlem Gülbahar

Learn More
BACKGROUND AND OBJECTIVES Obstructive sleep apnea syndrome (OSAS) is a common disorder characterized by numerous episodes of absence of respiratory flow during sleep, which can be followed by a decrease in SaO2, which is rapidly normalized when ventilation resumes. We hypothesize that this hypoxia-reoxygenation phenomena may affect the generation of(More)
PURPOSE We investigated the effect of eritoran, a Toll-like receptor 4 antagonist, on retinochoroidal inflammatory damage in an endotoxin-induced inflammatory rat model. METHODS Endotoxin-induced inflammatory model was obtained by intraperitoneal injection of 1.5 mg/kg lipopolysaccharide (LPS). Group 1 had control rats; in groups 2-3 LPS and 0.5 mg/kg(More)
Auditory evoked potentials in a newborn Wistar rat model of hyperbilirubinemia Abstract Introduction: Hyperbilirubinemia is a common health problem in newborns. Its effects can be different according to the level and duration of the hyperbilirubinemia. The toxic effect of bilirubin on the auditory system can be seen as a sensory neural hearing loss or(More)
INTRODUCTION Hyperbilirubinemia is a common health problem in newborns. Its effects can be different according to the level and duration of the hyperbilirubinemia. The toxic effect of bilirubin on the auditory system can be seen as a sensory neural hearing loss or auditory neuropathy spectrum disorder (ANSD). OBJECTIVE The purpose of our study was to(More)
OBJECTIVE Tumor necrosis factor alpha (TNF-α) have proven effects in pathogenesis of neuroinflammation after spinal cord injury (SCI). Current study is designed to evaluate the effects of an anti-TNF-α agent, adalimumab, on spinal cord clip compression injury in rats. METHODS Thirty two male adult Wistar rats were divided into four groups (sham, trauma,(More)
The aim of this study was to investigate the effects of valproate and carbamazepine, on renal glomerular and tubular functions. The patient group comprised 54 children with new-onset epilepsy treated with valproate (n = 30) and carbamazepine (n = 24). Twenty-six healthy children were in the control group. The serum creatinine and cystatin C levels and(More)
OBJECTIVES In addition to its roles in the stimulation of growth hormone secretion and the regulation of appetite and metabolism, ghrelin exerts immunomodulatory, anti-inflammatory and antioxidant actions in several organ systems. In this study, we investigated the effects of ghrelin on the healing of experimental colonic anastomoses. METHODS Wistar rats(More)
  • Hemodiyaliz Hastalarında, Orexin-A Düzeyleri, Nutrisyonel Durum, Uyku Kalitesi, Arasındaki İlişki, Ozlem Gulbahar +9 others
  • 2010
Objective: Symptoms such as anorexia and sleep disturbances are common and cause a significant reduction in quality of life in hemodialysis patients. Orexin-A, which is a neuropeptide produced in lateral hypothalamic neurons and involved in regulation of feeding behavior, energy metabolism and sleep-wake cycle, is a good candidate to play a role in sleep(More)
  • 1