Özen Sercan Alp

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We are thankful for an excellent opportu­ nity to expand on our Review (Organization of immuno logical memory by bone mar­ row stroma. Nat. Rev. Immunol. 10, 193–200 (2010))1 that has been provided by the correspondence from Francesca Di Rosa (Maintenance of memory T cells in the bone marrow: survival or homeostatic proliferation? Nat. Rev. Immunol.(More)
It is current belief that numbers of CD8+ memory T lymphocytes in the memory phase of an immune response are maintained by homeostatic proliferation. Here, we compare the proliferation of CD8+ memory T lymphocytes, generated by natural infections and by intentional immunization, in spleen and bone marrow (BM). Fifty percent of CD8+ memory T lymphocytes in(More)
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