Ólafur Gudmundsson

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OBJECTIVES The aim of this study was to develop and test, for the first time, a multivariate diagnostic classifier of attention deficit hyperactivity disorder (ADHD) based on EEG coherence measures and chronological age. SETTING The participants were recruited in two specialised centres and three schools in Reykjavik. PARTICIPANTS The data are from a(More)
In a study of ADHD symptoms in the relatives of probands diagnosed with ADHD, the validity of self-reported and informant-reported symptoms in childhood and adulthood was investigated with a semistructured diagnostic interview, the Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS) adapted for adults, as a criterion. The(More)
The persistence of common, heritable psychiatric disorders that reduce reproductive fitness is an evolutionary paradox. Here, we investigate the selection pressures on sequence variants that predispose to schizophrenia, autism, bipolar disorder, major depression and attention deficit hyperactivity disorder (ADHD) using genomic data from 150,656 Icelanders,(More)
OBJECTIVE ADHD is a well known psychiatric disorder that begins in childhood and frequently persists into adulthood. In the last decade numerous studies have shown the importance of genetic factors in the etiology of ADHD. However other etiological factors seem to be involved. The aim of this study was to examine the frequency of some possible etiological(More)
BACKGROUND Large, rare chromosomal deletions and duplications known as copy number variants (CNVs) have been implicated in neurodevelopmental disorders similar to attention-deficit hyperactivity disorder (ADHD). We aimed to establish whether burden of CNVs was increased in ADHD, and to investigate whether identified CNVs were enriched for loci previously(More)
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