É. G. Gromova

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Cuscohygrine dimethiodide is a pharmacological analog of a locally produced product Hygronium [4, 5], which is widely used in surgical practice for controlled hypotony. Hethyl iodide served as the methylating agent in its preparation. During the synthesis of certain ganglion-blocking agents, methyl iodide was successfully replaced by methyl(More)
The aim of this investigation was to find active compounds in the isatin series, and to establish relationships between structure and antiinflammatory activity. The isatin thioacyl hydrazones (I-IV) have been obtained, having different radicals attached to the indole nitrogen, and also the number, structures, and positions of the hydrazone groupings at C(2(More)
The activity of the pituitary-adrenal system was determined by the number of 17-hydroxycorticosteroids and eosinophils in the blood. As demonstrated, nutritional stimuli (meat, milk, bread) caused a rise in the 17-hydroxycorticosteroid concentration and reduction in the number of eosinophils. The analysis of the mechanism of stimulation of the system(More)
It was shown that the above-ground portion of certain forms of scopoline (Himalayan scopoline [1-3] and particularly Tangutskii scopoline [4=7], which is being introduced into cultivation at the present time) can serve as the source of scopolamine, atropine, and hyoscyamine. A large amount the liquid, the pharmacolocially inactive [8] alkaloid kuskgigrin(More)
The content of adrenalin and noradrenalin was determined in tissues of the heart, adrenals, spleen, and brain of rats with experimental myocardial infarction. A considerable fall in the tissue catecholamine level was found. Malaben restores the normal catecholamine content in the tissues in myocardial infarction, posibly as a result of the antihitamine(More)
Chemistry in the Design of New Drugs [in Russian], Riga (1982), p. 147. 8. E. K. Fields, J. Am. Chem. Soc., 74, 1528"1531 (1952). 9. M. R. }~rthy and P. A. Ranjekar, J. Chromatog., 76, 337-343 (1973). i0. J. R. Praes, International Publishers Annual Drug Data Report, Vol. 3, Barcelona (1981). ii. K. Smith and W. Kirkpatrick (editors), Ribavirin. A Broad(More)
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