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Combined systemic administration of morphine and magnesium sulfate attenuates pain-related behavior in mononeuropathic rats
Involvement of NMDA receptors and nitric oxide in the thermoregulatory effect of morphine in mice
- A. Ulugol, T. Dost, D. Dokmeci, M. Akpolat, Ç. H. Karadağ, I. Dokmeci
- BiologyJournal of Neural Transmission
The results further support the relationship between NO and NMDA receptors and suggest a possible role of NMDA-NO pathway in the thermoregulatory effect of morphine.
The Protective Effect of Curcumin on Ionizing Radiation-induced Cataractogenesis in Rats.
Curcumin has antioxidant and radioprotective properties and is likely to be a valuable agent for protection against ionizing radiation and may be used as an antioxidant and Radioprotector against radiation-induced cataractogenesis.
Asymmetric dimethylarginine levels in thyroid diseases
- E. Arikan, Ç. H. Karadağ, S. Guldıken
- Medicine, BiologyJournal of endocrinological investigation
- 4 December 2006
Not only hyperthyroidism but also hypothyroidism was associated with alterations ofADMA and SDMA metabolism, and there was a relationship between ADMA and L-arginine inHypothyroid patients, and ADMA was significantly related to L- arginine, total cholesterol, and LDL.
Descending serotonergic and noradrenergic systems do not regulate the antipruritic effects of cannabinoids*
- Z. G. Todurga, O. Gunduz, Ç. H. Karadağ, A. Ulugol
- Biology, MedicineActa Neuropsychiatrica
- 8 April 2016
Findings indicate that cannabinoids dose-dependently reduce serotonin-induced scratching behaviour and neurotoxic destruction of descending inhibitory pathways does not mediate this antipruritic effect of WIN 55,212-2.
Evaluation of Iloprost to Prevent Vasospasm in Coronary Artery Bypass Grafts
- T. Ege, O. Gur, Ç. H. Karadağ, E. Duran
- MedicineThe Journal of international medical research
- 1 October 2010
It is suggested that local administration of iloprost has a role in relieving graft vasospasm during harvesting and preparation for coronary artery bypass grafting.
Effects of losartan on glycerol-induced myoglobinuric acute renal failure in rats.
There is no positive effect of losartan on the pathogenesis of mARF, and it is found that levels of urea, creatinine, and potassium, in serum samples and MDA and ADMA in renal tissue were increased in 3rd group when it’s compared with the 1st group.
Effects of hippocampal histone acetylation and HDAC inhibition on spatial learning and memory in the Morris water maze in rats
- R. D. Topuz, O. Gunduz, E. Taştekin, Ç. H. Karadağ
- Biology, PsychologyFundamental & clinical pharmacology
- 1 April 2020
Sodium butyrate partially ameliorated learning and memory disruption induced by scopolamine; however, the histone deacetylase inhibitors can be new treatment agent for cognitive disorders.
Lack of effect of ceftriaxone, a GLT-1 transporter activator, on spatial memory in mice
Modulatory role of the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine (ADMA), in morphine tolerance and dependence in mice
The results suggest that endogenous plasma ADMA, SDMA, l-homo arginine and l-arginine levels remain unchanged during the development of morphine tolerance and dependence, and are not associated with these phenomena.