Álvaro Vigo

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To examine the association of low-grade systemic inflammation with diabetes, as well as its heterogeneity across subgroups, we designed a case-cohort study representing the approximately 9-year experience of 10,275 Atherosclerosis Risk in Communities Study participants. Analytes were measured on stored plasma of 581 incident cases of diabetes and 572(More)
The aim of this study was to investigate the relationship between feeding practices in the first year of life and the occurrence of severe early childhood caries (S-ECC) at 4 years of age. A birth cohort study (n = 500) was conducted in children who were born within the public health system in São Leopoldo, Brazil. Feeding practices were assessed using(More)
The aim of this study was to investigate the association of leptin levels with incident diabetes in middle-aged adults, taking into account factors purportedly related to leptin resistance. We conducted a case–cohort study (570 incident diabetes cases and 530 non-cases) representing the 9-year experience of 10,275 participants of the Atherosclerosis Risk in(More)
OBJECTIVE To evaluate commonality of risk factor profiles of women who develop gestational diabetes and pre-eclampsia. METHODS Prospective cohort study in prenatal clinics of the Brazilian Unified Health System in six state capitals. 4.766 pregnant women between 20 to 48 years old were consecutively enrolled between 20th and 28th gestational weeks.(More)
BACKGROUND To investigate the hypothesis that intrauterine growth restriction might produce a longstanding pro-inflammatory tendency, we investigated the association of low birth weight with blood levels of markers of inflammation and endothelial activation in middle-aged adults. METHODS The ARIC Study enrolled subjects aged 45-64 years sampled from four(More)
AIMS To evaluate the diagnostic criteria of the International Association of Diabetes and Pregnancy Study Groups (IADPSG) and alternative criteria in terms of resultant prevalence of gestational diabetes mellitus (GDM) and measures of diagnostic impact. METHODS The Brazilian Gestational Diabetes Study (EBDG) is a cohort of pregnant women enrolled(More)
OBJECTIVE To evaluate the association of changes in smoking habit with maternal weight gain. STUDY DESIGN We questioned 4000 pregnant women > or =20 years about previous and current smoking habits during a second trimester visit to general prenatal clinics in 6 Brazilian cities, from 1991 to 1995, and followed their weight, through chart review, to term.(More)
Chronic Non-Communicable Diseases are the main source of disease burden in Brazil. In 2011, the Brazilian Ministry of Health launched the Strategic Plan of Action for Management of Chronic Non-Communicable Diseases focusing on population-based interventions to manage cardiovascular diseases, diabetes, cancer, and chronic respiratory diseases mainly through(More)
To the Editor: We thank Snijder et al. for sharing their data from the Hoorn Study [1] and for their interpretation of the protective associations we reported between leptin and incident diabetes in middle-aged adults from the Atherosclerosis Risk in Communities (ARIC) study [2]. The findings of Snijder et al. differ from those we reported. First, in their(More)
INTRODUCTION The prevalence of diabetes is increasing worldwide. The objective of this study is to estimate the prevalence of self-reported diabetes in Brazilian adults and to describe its population correlates as well as the clinical characteristics of the reported cases. METHODS We analyzed basic and supplementary data of 54.144 subjects participating(More)