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The cerebral projection of vestibular signaling was studied by using PET with a special differential experimental protocol. Caloric vestibular stimulation (CVS)-induced regional cerebral blood flow (rCBF) changes were investigated in two populations. Butanol perfusion scans were carried out on six healthy volunteers and on six patients following the removal(More)
We show that two results on covering of edge colored graphs by monochromatic connected parts can be extended to partitioning. We prove that for any 2-edge-colored non-trivial r-uniform hypergraph H, the vertex set can be partitioned into at most α(H) − r + 2 monochromatic connected parts, where α(H) is the maximum size of a set of vertices that does not(More)
BACKGROUND Most cases of vertigo are attributable to both peripheral and central vestibular disorders. Therefore, it would be of interest to determine whether a combination therapy having both peripheral and central actions would translate into more efficient symptom relief. OBJECTIVE This study was conducted to evaluate the efficacy and tolerability of a(More)
P-glycoprotein (Pgp, ABCB1) is one of the active efflux pumps that are able to extrude a large variety of chemotherapeutic drugs from the cells, causing the phenomenon of multidrug resistance. It has been shown earlier that the combined application of a class of Pgp modulators (e.g. cyclosporine A and SDZ PSC 833) used at low concentrations and UIC2(More)
Formation of immunological synapse (IS), the interface between T cells and antigen presenting cells, is a crucial step in T cell activation. This conjugation formation results in the rearrangement and segregation of a set of membrane bound and cytosolic proteins, including that of the T cell receptor, into membrane domains. It was showed earlier that Kv1.3,(More)
Margatoxin (MgTx), an alpha-KTx scorpion toxin, is considered a selective inhibitor of the Kv1.3K + channel. This peptide is widely used in ion channel research; however, a comprehensive study of its selectivity with electrophysiological methods has not been published yet. The lack of selectivity might lead to undesired side effects upon therapeutic(More)
The evaluation of cochleovestibular dysfunction in psychiatric patients often causes a difficult problem in neurootological experience. The authors discuss here the neurobiological basis of panic disorders and cochleovestibular dysfunction. In this multicenter study, we examined 63 patients with vertigo and panic disease. Twenty patients with primary panic(More)
Körner and Malvenuto asked whether one can find`n n/2 ´ linear orderings (i. e., permutations) of the first n natural numbers such that any pair of them place two consecutive integers somewhere in the same position. This led to the notion of graph-different permutations. We extend this concept to directed graphs, focussing on orientations of the(More)
The paper outlines the European and local situation regarding the use of virtual learning environments in technical teacher training and retraining and presents an overview of the content and methods of the continuing education for technical teachers. Introducing and running retraining courses on virtual learning environments including IT and its multimedia(More)